Urinary tract infections are a serious health problem affecting millions of people each year.
Second Month of Pregnancydog urinary tract infection symptomsgymnastics-gripsconcept 2 rowing machine reviewsInfections of the urinary tract are common -- only respiratory infections occur more often.
urinary tract infections (UTI's) account for about 8 million doctor visits.
to UTI's for reasons that are poorly understood.
lifetime. male urinary tract infection symptoms
The Urinary Tract
The key players in the
system are the kidneys, a pair of purplish-brown organs located below the ribs toward the middle of
the back.
of salts and other substances in the blood, and produce a hormone that aids the formation of red
blood cells.
chamber in the lower abdomen. Urine is stored in the bladder and emptied through the urethra.
The average adult passes about a quart and a half of urine each day. The amount of urine varies,
depending on the fluids and foods a person consumes. The volume formed at night is about half that
Normal urine is sterile. It contains fluids, salts, and waste products, but it is free of bacteria, viruses,
and fungi. An infection occurs when microorganisms, usually bacteria from the digestive tract, cling to
Most infections arise from one type of bacteria,
Escherichia coli (E. coli), which normally live in the colon.
An infection limited to the urethra is called urethritis. From there bacteria often move on
to the bladder, causing a bladder infection (cystitis). symptoms of urinary tract infection in childrenIf the infection is not treated promptly, bacteria
may then go up the ureters to infect the kidneys (pyelonephritis).
Microorganisms called Chlamydia and Mycoplasma may also cause UTI's in both men and women,
but these infections tend to remain limited to the urethra and reproductive system. Unlike E. coli,
Chlamydia and Mycoplasma may be sexually transmitted, and infections require treatment of both
partners. The ureters and
bladder normally prevent urine from backing up toward the kidneys, and the flow of urine from the
bladder helps wash bacteria out of the body. In men, the prostate gland produces secretions that slow
bacterial growth. In both sexes, immune defenses also prevent infection. Despite these safeguards,
Who is at Risk
Some people are more prone to getting a UTI than others.
An enlarged
prostate gland also can slow the flow of urine,
urinary tract infection symptoms thus raising the risk of infection. A common source of
A person who cannot void, is unconscious or
critically ill, often needs a catheter that stays in place for a long time.
especially the elderly or those with nervous system disorders who lose bladder control, may need a
Bacteria on the catheter can infect the bladder, so hospital staff take special care to
keep the catheter sterile and remove it as soon as possible.
Any
disorder that suppresses the immune system raises the risk of a urinary infection. UTI's may occur in
infants who are born with abnormalities of the urinary tract, which sometimes need to be corrected
with surgery. UTI's are rarely seen in boys and young men.
UTI's gradually increases with age.
than men.
bladder. Also, a woman's urethral opening is near sources of bacteria from the anus and vagina. For
many women, sexual intercourse seems to trigger an infection, although the reasons for this linkage are
unclear.
than women who use other forms of birth control. Recently, researchers found that women whose
partners use a condom with spermicidal foam also tend to have growth of E. coli bacteria in the
vagina.
Recurrent Infections
Nearly 20 percent of women who have a UTI will have
another, and 30 percent of those will have yet another. Of the last group, 80 percent will have
Usually, the latest infection stems from a strain or type of bacteria that is different from
the infection before it, indicating a separate infection. (Even when several UTI's in a row are due to E.
coli, slight differences in the bacteria indicate distinct infections.)
Research funded by the National Institutes of Health (NIH) suggests that one factor behind recurrent
UTI's may be the ability of bacteria to attach to cells lining the urinary tract. A recent NIH funded
study has also shown that women with recurrent UTI's tend to have certain blood types. Some
scientists speculate that women with these blood types are more prone to UTI's because the cells
lining the vagina and urethra may allow bacteria to attach more easily. Further research will show
Infections in Pregnancy
Pregnant women seem no more prone to UTI's than other women.
it is more likely to travel to the kidneys. According to some reports, about 2 to 4 percent of pregnant
women develop a urinary infection.
the urinary tract during pregnancy make it easier for bacteria to travel up the ureters to the kidneys.
this reason, many doctors recommend periodic testing of urine.
Symptoms
These may include a
frequent urge to urinate and a painful, burning feeling in the area of the bladder or urethra during
It is not unusual to feel bad all over-tired, shaky, washed out -- and to feel pain even when
not urinating.
experience a fullness in the rectum. It is common for a person with a urinary infection to complain that,
despite the urge to urinate, only a small amount of urine is passed. The urine itself may look milky or
cloudy, even reddish if blood is present. A fever may mean that the infection has reached the kidneys.
Other symptoms of a kidney infection include pain in the back or side below the ribs, nausea, or
In children, symptoms of a urinary infection may be overlooked or attributed to another
disorder.
there is a change in the child's urinary pattern.
You
"midstream" sample of urine in a sterile container. (This method of collecting urine helps prevent
the sample is sent to a laboratory, although some doctors' offices are equipped to do the testing.
In the urinalysis test, the urine is examined for urinary tract infection symptomswhite and red blood cells and bacteria. Then the
bacteria are grown in a culture and tested against different antibiotics to see which drug best destroys
This last step is called a sensitivity test.
Some microbes, like Chlamydia and Mycoplasma, can only be detected with special bacterial cultures.
A doctor suspects one of these infections when a person has symptoms of a UTI and pus in the urine,
but a standard culture fails to grow any bacteria.
When an infection does not clear up with treatment and is traced to the same strain of bacteria, the
doctor will order a test that makes images of the urinary tract. One of these tests is an intravenous
pyelogram (IVP), which gives x-ray images of the bladder, kidneys, and ureters. An opaque dye
visible on x-ray film is injected into a vein, and a series of x-rays are taken. The film shows an outline
of the urinary tract, revealing even small changes in the structure of the tract.
If you have recurrent infections, your doctor also may recommend an ultrasound exam, which gives
pictures from the echo patterns of soundwaves bounced back from internal organs.
test is cystoscopy. A cystoscope is an instrument made of a hollow tube with several lenses and a
UTI's are treated with antibacterial drugs. The choice of drug and length of treatment depends on the
uncomplicated UTI's are trimethoprim (Trimpex), trimethoprim/sufamethoxazole (Bactrim, Septra,
ampicillin. Often, a UTI can be cured with 1 or 2 days of treatment if the infection is not complicated
by an obstruction or nervous system disorder. Still, many doctors ask their patients to take antibiotics
for a week or two to assure that the infection has been cured.
recommended for some groups of patients, for example, those who have delayed treatment or have
signs of a kidney infection, patients with diabetes or structural abnormalities, or men who have
prostate infections. Longer treatment is also needed by patients with infections caused by
Mycoplasma or Chlamydia, which are usually treated with tetracycline, trimethoprim/sulfamethoxazole
(TMP/SMZ), or doxycycline. A follow-up urinalysis helps to confirm that the urinary tract is
It is important to take the full course of
treatment because symptoms may disappear before the infection is fully cleared.
drugs on their own.
effective as 6 weeks of treatment with the same drug in women with kidney infections that did not
involve an obstruction or nervous system disorder. In such cases, kidney infections rarely lead to
kidney damage or kidney failure unless they go untreated.
Various drugs are available to relieve the pain of a UTI. A heating pad or a warm bath may also help.
Most doctors suggest that drinking plenty of water helps cleanse the urinary tract of bacteria. For the
(And one of the best things a smoker
can do for his or her bladder is to quit smoking.
cancer.)
About 4 out of 5 women who have a UTI get another in 18 months.
about one of the following treatment options:
(If
taken at bedtime, the drug remains in the bladder longer and may be more effective.)
NIH-supported research at the University of Washington has shown this therapy to be effective
without causing serious side effects.
Take a single dose of an antibiotic after sexual intercourse.
Take a short course (1 or 2 days) of antibiotics when symptoms appear.
The
strips detect nitrite, which is formed when bacteria change nitrate the urine to nitrate. The test can
detect about 90 percent of UTI's and may be useful for women who have recurrent infections.
amounts inhibits the growth of some bacteria by acidifying the urine. Vitamin C (Ascorbic Acid)
Wipe from front to back to prevent bacteria around the anus from entering the vagina or urethra;
Take showers instead of tub baths;
Avoid using feminine hygiene sprays and scented douches, which may irritate the urethra.
A pregnant woman who develops a UTI should be treated promptly to avoid premature delivery of her
Some antibiotics are not safe to take during
pregnancy. In selecting the best treatments, doctors consider various factors such as the drug's
effectiveness, the stage of pregnancy, the mother's health, and potential effects on the fetus.
Complicated Infections
and correcting the underlying problem, sometimes with surgery. If the root cause goes untreated, this
group of patients is at risk of kidney damage. Also, such infections tend to arise from a wider range of
bacteria, and sometimes from more than one type of bacteria at a time.
UTI's are unusual in men. They usually stem from an obstruction -- for example, a urinary stone or
The first step is to identify the
infecting organism and the drugs to which it is sensitive.
symptoms of urinary tract infection in childrenUsually, doctors recommended lengthier
therapy in men than in women, in part to prevent infections of the prostate gland. Prostate infections
(prostatitis) are harder to cure because antibiotics are unable to penetrate infected prostate tissue
effectively.
selected antibiotic.
Research in Urinary System Disorders
The NIH conducts and supports a variety of research in diseases of the kidney and urinary tract. The
knowledge gained from these studies is advancing scientific understanding of why UTI's develop and
is leading to improved methods of diagnosing, treating, and preventing infections.
Information provided by the NIH & NIDDK